Characterization of the mouse Cblc/Cbl3 gene

被引:5
作者
Fiore, F [1 ]
Ollendorff, V [1 ]
Birnbaum, D [1 ]
机构
[1] INSERM, U119, Oncol Mol Lab, F-13009 Marseille, France
关键词
D O I
10.1006/bbrc.2000.4116
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domains. Mouse Cblc mRNA is expressed in embryo and adult tissues and has a rather ubiquitous distribution. (C) 2001 Academic Press.
引用
收藏
页码:182 / 187
页数:6
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