Lack of resistant mutation development after receiving short-course zidovudine plus lamivudine to prevent mother-to-child transmission

被引：6

作者：

Chokephaibulkit, K ^{[1
]}

Chaisilwattana, P

Vanprapar, N

Phongsamart, W

Sutthen, R

机构：

[1] Mahidol Univ, Siriraj Hosp, Fac Med, Dept Pediat, Bangkok 10700, Thailand

[2] Mahidol Univ, Siriraj Hosp, Fac Med, Dept Obstet & Gynecol, Bangkok 10700, Thailand

[3] Mahidol Univ, Siriraj Hosp, Fac Med, Dept Microbiol, Bangkok 10700, Thailand

来源：

AIDS | 2005年 / 19卷 / 11期

关键词：

D O I：

10.1097/01.aids.0000176226.63732.71

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A short-course regimen of zidovudine plus lamivudine starting from 34 weeks' gestation in pregnant women to prevent mother-to-child HIV infection, and discontinued after delivery, was evaluated for the development of resistance at 6 weeks postpartum. No resistant mutation was found in 32 women. One of the three infected infants carried the M184V and K219Q mutations.

引用

页码：1231 / 1233

页数：3

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