Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy .1. System development and control

被引：113

作者：

Hailey, PA

Doherty, P

Tapsell, P

Oliver, T

Aldridge, PK

机构：

[1] PFIZER LTD,CENT RES,DISCOVERY HQ,SANDWICH CT13 9NJ,KENT,ENGLAND

[2] PFIZER INC,CENT RES,ANALYT RES & DEV,GROTON,CT 06340

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1996年 / 14卷 / 05期

关键词：

near-infrared spectroscopy; on-line analysis; fibre-optics; blending; chemometrics; pharmaceutical analysis; process control;

D O I：

10.1016/0731-7085(95)01674-0

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An automated system for the on-line monitoring of powder blending processes is described. The system employs near-infrared (NIR) spectroscopy using fibre-optics and a graphical user interface (GUI) developed in the LabVIEW environment. The complete supervisory control and data analysis (SCADA) software controls blender and spectrophotometer operation and performs statistical spectral data analysis in real time. A data analysis routine using standard deviation is described to demonstrate an approach to the real-time determination of blend homogeneity.

引用

页码：551 / 559

页数：9

共 9 条

[1]

ALDRIDGE PK, 1993, AOAC M OCT

[2] STANDARD NORMAL VARIATE TRANSFORMATION AND DE-TRENDING OF NEAR-INFRARED DIFFUSE REFLECTANCE SPECTRA [J].