Multifunctional mesoporous silica nanoparticles for intracellular labeling and animal magnetic resonance imaging studies

被引：166

作者：

Wu, Si-Han ^{[2
]}

Lin, Yu-Shen ^{[2
]}

Hung, Yann ^{[2
]}

Chou, Yi-Hsin ^{[1
]}

Hsu, Yi-Hua ^{[1
]}

Chang, Chen ^{[1
]}

Mou, Chung-Yuan ^{[2
]}

机构：

[1] Acad Sinica, Inst Biomed Sci, Taipei 115, Taiwan

[2] Natl Taiwan Univ, Dept Chem, Taipei 106, Taiwan

来源：

CHEMBIOCHEM | 2008年 / 9卷 / 01期

关键词：

cell tracking; imaging agents; magnetic resonance imaging; mesoporous materials; nanoparticles;

D O I：

10.1002/cbic.200700509

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

(Figure Presented) Light up your cells: Multifunctional mesoporous silica nanoparticles were successfully demonstrated to be excellent bimodal imaging probes for intracellular labeling and as in vivo magnetic resonance imaging contrast agents. These studies provide the basis for the use of mesoporous silica nanoparticles as diagnostic tools and therapeutic drug carriers. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：53 / 57

页数：5

共 26 条

[1]

Bremer C, 1999, JMRI-J MAGN RESON IM, V10, P461, DOI 10.1002/(SICI)1522-2586(199909)10:3<461::AID-JMRI30>3.3.CO

[2]

2-X

[3] The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles 3T3-L1 cells and human mesenchymal stem cells [J].