New concepts in the pathogenesis of atopic dermatitis

被引：79

作者：

Leung, DYM

Jain, N

Leo, HL

机构：

[1] Univ Colorado, Hlth Sci Ctr, Div Pediat Allergy Immunol, Natl Jewish Med & Res Ctr, Denver, CO USA

[2] Univ Colorado, Hlth Sci Ctr, Dept Pediat, Denver, CO USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2003年 / 15卷 / 06期

关键词：

D O I：

10.1016/j.coi.2003.09.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Atopic dermatitis is a chronic, relapsing, inflammatory skin disease that is characterized by pruritic, eczematoid skin lesions. The disease results from interactions between susceptibility genes, the host environment, skin barrier defects, susceptibility to infection and immunological factors. An increased prevalence of atopic dermatitis has generated increased interest and research into each of these areas, and new treatment strategies are being developed based upon an increased understanding of these issues.

引用

页码：634 / 638

页数：5

共 46 条

[41] Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects [J].