Syndecan-4 and focal adhesion function

被引：191

作者：

Woods, A ^{[1
]}

Couchman, JR

机构：

[1] Univ Alabama Birmingham, Dept Cell Biol, Birmingham, AL 35294 USA

[2] Imperial Coll Sch Med, Div Biomed Sci, London SW7 2AZ, England

来源：

CURRENT OPINION IN CELL BIOLOGY | 2001年 / 13卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(00)00254-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Two groups have now reported the viability of mice that lack syndecan-4. These mice have wound healing/angiogenesis problems, and fibroblasts from these animals differ in adhesion and migration from normal. This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration.

引用

页码：578 / 583

页数：6

共 59 条

[1]

Baciu PC, 2000, J CELL SCI, V113, P315

[2] Functions of cell surface heparan sulfate proteoglycans [J].

Bernfield, M ;

Götte, M ;

Park, PW ;

Reizes, O ;

Fitzgerald, ML ;

Lincecum, J ;

Zako, M .

ANNUAL REVIEW OF BIOCHEMISTRY, 1999, 68 :729-777

[3] Rho GTPases and their effector proteins [J].

Bishop, AL ;

Hall, A .

BIOCHEMICAL JOURNAL, 2000, 348 (02) :241-255

[4]

Brakebusch C, 1997, J CELL SCI, V110, P2895

[5] Focal adhesions, contractility, and signaling [J].

Burridge, K ;

ChrzanowskaWodnicka, M .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 1996, 12 :463-518

[6]

Carey DJ, 1997, BIOCHEM J, V327, P1

[7] Syndecan-4 is a primary-response gene induced by basic fibroblast growth factor and arterial injury in vascular smooth muscle cells [J].

CizmeciSmith, G ;

Langan, E ;

Youkey, J ;

Showalter, LJ ;

Carey, DJ .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1997, 17 (01) :172-180

[8]

Couchman JR, 2001, INT REV CYTOL, V207, P113

[9] Dissection of pathways implicated in integrin-mediated actin cytoskeleton assembly - Involvement of protein kinase C, Rho GTPase, and tyrosine phosphorylation [J].

Defilippi, P ;

Venturino, M ;

Gulino, D ;

Duperray, A ;

Boquet, P ;

Fiorentini, C ;

Volpe, G ;

Palmieri, M ;

Silengo, L ;

Tarone, G .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (35) :21726-21734

[10]

Echtermeyer F, 1999, J CELL SCI, V112, P3433

← 1 2 3 4 5 6 →