Liquid chromatography-(tandem) mass spectrometry for the follow-up of the elimination of persistent pharmaceuticals during wastewater treatment applying biological wastewater treatment and advanced oxidation

被引：95

作者：

Gebhardt, Wilhelm ^{[1
]}

Schroeder, Horst Fr. ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen Univ, Environm Analyt Lab, Inst Environm Engn, D-52056 Aachen, Germany

来源：

JOURNAL OF CHROMATOGRAPHY A | 2007年 / 1160卷 / 1-2期

关键词：

advanced oxidation process (AOP); biological wastewater treatment; degradation products; mass and tandem mass spectrometry; polar pharmaceuticals;

D O I：

10.1016/j.chroma.2007.05.075

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The persistent and hardly eliminable pharmaceutical compounds carbamazepine, diazeparn, diclofenac and clofibric acid were monitored in municipal wastewater by electrospray LC-MS and LC-MS-MS in positive and negative mode under high resolution and high mass accuracy conditions. While biological treatment by conventional and membrane bioreactors failed, the advanced oxidation methods using ozone (O-3), O-3/UV or hydrogen peroxide in combination with LTV (H2O2/UV) successfully led to the complete elimination of these compounds. Target compounds could be confirmed as permanently present pollutants in Aachen-Soers wastewater in concentrations between 0.006 and 1.9 mu g l(-1). Pharmaceuticals were determined after extraction using either C-18 solid-phase extraction or by directly injecting them into the column without pre-concentration, achieving limits of quantification of 0.001 or 0.00001 mu g l(-1), respectively. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：34 / 43

页数：10

共 33 条

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