Investigations of polymorphism and pseudo-polymorphism in pharmaceuticals by combined thermoanalytical techniques

被引：92

作者：

Giron, D ^{[1
]}

机构：

[1] Novartis Pharma AG, Chem & Analyt Dev, Basel, Switzerland

来源：

JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY | 2001年 / 64卷 / 01期

关键词：

pharmaceuticals; polymorphism; pseudo-polymorphism;

D O I：

10.1023/A:1011572610005

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

This article summarizes the main features in the investigation of polymorphic behaviour of pharmaceuticals and emphasizes the role of combined thermoanalytical techniques for proper interpretation of complex problems. The examples illustrate the quality of information gained in relation to thermodynamic and kinetic factors.

引用

页码：37 / 60

页数：24

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