Clinicopathological features of myeloid/natural killer (NK) cell precursor acute leukemia

被引：20

作者：

Inaba, T ^{[1
]}

Shimazaki, C

Sumikuma, T

Ochiai, N

Okano, A

Hatsuse, M

Ashihara, E

Kobayashi, Y

Rin, K

Murakami, S

Haruyama, H

Fujita, N

Nakagawa, M

机构：

[1] Kyoto Prefectural Univ Med, Dept Clin Lab & Med, Kamigyo Ku, Kyoto 6028566, Japan

[2] Kyoto Prefectural Univ Med, Dept Med 2, Kamigyo Ku, Kyoto 6028566, Japan

[3] Kyoto Prefectural Univ Med, Dept Med 1, Kamigyo Ku, Kyoto 6028566, Japan

[4] Akashi Municipal Hosp, Dept Med, Akashi, Hyogo 6728501, Japan

[5] Shakaihoken Kyoto Hosp, Dept Med, Kyoto 6038151, Japan

来源：

LEUKEMIA RESEARCH | 2001年 / 25卷 / 02期

关键词：

myeloid/natural killer cell precursor acute leukemia; AML-M0; CD56; trisomy; 10;

D O I：

10.1016/S0145-2126(00)00099-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Four patients (three males and one female) were diagnosed as myeloid/natural killer (NK) cell precursor acute leukemia in our department. Two patients showed the extramedullary involvement at initial presentation. Leukemic cells expressed CD7, CD33, CD45 and CD56 in all patients. Additionally, CD13, CD34, HLA-DR, cytoplasmic CD3 and myeloperoxidase were expressed in some patients. Trisomy 10 was found in two patients, which has not been reported in this disease. Therefore, myeloid/NK cell precursor acute leukemia might be rather heterogeneous especially in chromosomal abnormality though it seemed to constitute the distinct clinical entity among acute myeloid leukemia of MO subtype. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：109 / 113

页数：5

共 18 条

[1] CHARACTERIZATION AND CHROMOSOMAL LOCALIZATION OF THE HUMAN PROTOONCOGENE BMI-1 [J].