Influenza A viruses: new research developments

被引：489

作者：

Medina, Rafael A. ^{[1
,2
]}

Garcia-Sastre, Adolfo ^{[1
,2
,3
]}

机构：

[1] Mt Sinai Sch Med, Dept Microbiol & Global Hlth, New York, NY 10029 USA

[2] Mt Sinai Sch Med, Emerging Pathogens Inst, New York, NY USA

[3] Mt Sinai Sch Med, Dept Med, Div Infect Dis, New York, NY USA

来源：

NATURE REVIEWS MICROBIOLOGY | 2011年 / 9卷 / 08期

关键词：

PATHOGENIC AVIAN INFLUENZA; SWINE-ORIGIN; 2009; LOWER RESPIRATORY-TRACT; SIALIC-ACID RECEPTORS; PANDEMIC INFLUENZA; H5N1; VIRUS; NS1; PROTEIN; H1N1; SEASONAL INFLUENZA; HUMAN HOST;

D O I：

10.1038/nrmicro2613

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Influenza A viruses are zoonotic pathogens that continuously circulate and change in several animal hosts, including birds, pigs, horses and humans. The emergence of novel virus strains that are capable of causing human epidemics or pandemics is a serious possibility. Here, we discuss the value of surveillance and characterization of naturally occurring influenza viruses, and review the impact that new developments in the laboratory have had on our understanding of the host tropism and virulence of viruses. We also revise the lessons that have been learnt from the pandemic viruses of the past 100 years.

引用

页码：590 / 603

页数：14

共 153 条

[1] SEQUENCE RELATIONSHIPS AMONG THE HEMAGGLUTININ GENES OF 12 SUBTYPES OF INFLUENZA-A VIRUS [J].

AIR, GM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (12) :7639-7643

[2]

[Anonymous], PLOS CURRENTS INFLUE

[3] Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus [J].

Baskin, Carole R. ;

Bielefeldt-Ohmann, Helle ;

Tumpey, Terrence M. ;

Sabourin, Patrick J. ;

Long, James P. ;

Garcia-Sastre, Adolfo ;

Tolnay, Airn-E. ;

Albrecht, Randy ;

Pyles, John A. ;

Olson, Pam H. ;

Aicher, Lauri D. ;

Rosenzweig, Elizabeth R. ;

Murali-Krishna, Kaja ;

Clark, Edward A. ;

Kotur, Mark S. ;

Fornek, Jamie L. ;

Proll, Sean ;

Palermo, Robert E. ;

Sabourin, Carol L. ;

Katze, Michael G. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (09) :3455-3460

[4] Current concepts - Avian influenza A (H5N1) infection in humans [J].

Beigel, H ;

Farrar, H ;

Han, AM ;

Hayden, FG ;

Hyer, R ;

de Jong, MD ;

Lochindarat, S ;

Tien, NTK ;

Hien, NT ;

Hien, TT ;

Nicoll, A ;

Touch, S ;

Yuen, KY .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (13) :1374-1385

[5] The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus [J].

Brass, Abraham L. ;

Huang, I-Chueh ;

Benita, Yair ;

John, Sinu P. ;

Krishnan, Manoj N. ;

Feeley, Eric M. ;

Ryan, Bethany J. ;

Weyer, Jessica L. ;

van der Weyden, Louise ;

Fikrig, Erol ;

Adams, David J. ;

Xavier, Ramnik J. ;

Farzan, Michael ;

Elledge, Stephen J. .

CELL, 2009, 139 (07) :1243-1254

[6] Summary of Avian Influenza Activity in Europe, Asia, and Africa, 2006-2009 [J].

Brown, Ian H. .

AVIAN DISEASES, 2010, 54 (01) :187-193

[7] Molecular Analysis of H7 Avian Influenza Viruses from Australia and New Zealand: Genetic Diversity and Relationships from 1976 to 2007 [J].

Bulach, Dieter ;

Halpin, Rebecca ;

Spiro, David ;

Pomeroy, Laura ;

Janies, Daniel ;

Boyle, David B. .

JOURNAL OF VIROLOGY, 2010, 84 (19) :9957-9966

[8] Comparison of Pandemic (H1N1) 2009 and Seasonal Influenza, Western Australia, 2009 [J].

Carcione, Dale ;

Giele, Carolien ;

Dowse, Gary K. ;

Mak, Donna B. ;

Goggin, Leigh ;

Kwan, Kelly ;

Williams, Simon ;

Smith, David ;

Effler, Paul .

EMERGING INFECTIOUS DISEASES, 2010, 16 (09) :1388-1395

[9]

CDC, 2010, UPD CDC EST 2009 H1N

[10] Clinical and virological course of infection with haemagglutinin D222G mutant strain of 2009 pandemic influenza A (H1N1) virus [J].

Chan, Paul K. S. ;

Lee, Nelson ;

Joynt, Gavin M. ;

Choi, K. W. ;

Cheung, Jo L. K. ;

Yeung, Apple C. M. ;

Lam, Philip ;

Wong, Rity ;

Leung, Bo-Wah ;

So, Hing-Yu ;

Lam, Wai-Yip ;

Hui, David C. S. .

JOURNAL OF CLINICAL VIROLOGY, 2011, 50 (04) :320-324

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