The BDNF val66met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples

被引:30
作者
Li, Y
Rowland, C
Tacey, K
Catanese, J
Sninsky, J
Hardy, J
Powell, J
Lovestone, S
Morris, JC
Thal, L
Goate, A
Owen, M
Williams, J
Grupe, A
机构
[1] Celera Diagnost, Alameda, CA 94502 USA
[2] NIA, Bethesda, MD 20892 USA
[3] Kings Coll London, Inst Psychiat, Dept Neurosci, London WC2R 2LS, England
[4] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
[5] Univ Calif San Diego, Dept Neurosci, San Diego, CA 92103 USA
[6] Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USA
[7] Cardiff Univ, Wales Coll Med, Dept Psychol Med, Cardiff, Wales
关键词
D O I
10.1038/sj.mp.4001702
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:809 / 810
页数:3
相关论文
共 10 条
  • [1] Brain-derived neurotrophic factor genetic variants are not susceptibility factors to Alzheimer's disease in Italy
    Bagnoli, S
    Nacmias, B
    Tedde, A
    Guarnieri, BM
    Cellini, E
    Petruzzi, C
    Bartoli, A
    Ortenzi, L
    Sorbi, S
    [J]. ANNALS OF NEUROLOGY, 2004, 55 (03) : 447 - 448
  • [2] Polymorphism at codon 66 of the brain-derived neurotrophic factor gene is not associated with sporadic Alzheimer's disease
    Combarros, O
    Infante, J
    Llorca, J
    Berciano, J
    [J]. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2004, 18 (01) : 55 - 58
  • [3] The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    Egan, MF
    Kojima, M
    Callicott, JH
    Goldberg, TE
    Kolachana, BS
    Bertolino, A
    Zaitsev, E
    Gold, B
    Goldman, D
    Dean, M
    Lu, B
    Weinberger, DR
    [J]. CELL, 2003, 112 (02) : 257 - 269
  • [4] A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease
    Kunugi, H
    Ueki, A
    Otsuka, M
    Isse, K
    Hirasawa, H
    Kato, N
    Nabika, T
    Kobayashi, S
    Nanko, S
    [J]. MOLECULAR PSYCHIATRY, 2001, 6 (01) : 83 - 86
  • [5] Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family
    Li, Y
    Nowotny, P
    Holmans, P
    Smemo, S
    Kauwe, JSK
    Hinrichs, AL
    Tacey, K
    Doil, L
    van Luchene, R
    Garcia, V
    Rowland, C
    Schrodi, S
    Leong, D
    Gogic, G
    Chan, J
    Cravchik, A
    Ross, D
    Lau, K
    Kwok, S
    Chang, SY
    Catanese, J
    Sninsky, J
    White, TJ
    Hardy, J
    Powell, J
    Lovestone, S
    Morris, JC
    Thal, L
    Owen, M
    Williams, J
    Goate, A
    Grupe, A
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (44) : 15688 - 15693
  • [6] Brain-derived neurotrophic factor, apolipoprotein E genetic variants and cognitive performance in Alzheimer's disease
    Nacmias, B
    Piccini, C
    Bagnoli, S
    Tedde, A
    Cellini, E
    Bracco, L
    Sorbi, S
    [J]. NEUROSCIENCE LETTERS, 2004, 367 (03) : 379 - 383
  • [7] Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer's disease (LOAD) in Brazilian patients
    Nishimura, AL
    Oliveira, JRM
    Mitne-Neto, M
    Guindalini, C
    Nitrini, R
    Bahia, VS
    de Brito-Marques, PR
    Otto, PA
    Zatz, M
    [J]. JOURNAL OF MOLECULAR NEUROSCIENCE, 2004, 22 (03) : 257 - 260
  • [8] A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer's disease in patients lacking the Apolipoprotein E ε4 allele
    Riemenschneider, M
    Schwarz, S
    Wagenpfeil, S
    Diehl, J
    Müller, U
    Förstl, H
    Kurz, A
    [J]. MOLECULAR PSYCHIATRY, 2002, 7 (07) : 782 - 785
  • [9] Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset
    Tsai, SJ
    Hong, CJ
    Liu, HC
    Liu, TY
    Hsu, LE
    Lin, CH
    [J]. NEUROPSYCHOBIOLOGY, 2004, 49 (01) : 10 - 12
  • [10] Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease
    Ventriglia, M
    Chiavetto, LB
    Benussi, L
    Binetti, G
    Zanetti, O
    Riva, MA
    Gennarelli, M
    [J]. MOLECULAR PSYCHIATRY, 2002, 7 (02) : 136 - 137