Computational analyses of TBC protein family in eukaryotes

被引：8

作者：

Gao, Xinjiao

Jin, Changjiang

Xue, Yu ^{[1
]}

Yao, Xuebiao

机构：

[1] Hefei Natl Lab Phys Sci Microscale, Lab Cellular Dynam, Hefei 230027, Anhui, Peoples R China

[2] Univ Sci & Technol China, Hefei 230027, Anhui, Peoples R China

来源：

PROTEIN AND PEPTIDE LETTERS | 2008年 / 15卷 / 05期

关键词：

TBC domain; phylogenetic tree; USP6; polarized exocytosis; cell cycle; cytokinesis;

D O I：

10.2174/092986608784567483

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tre-2/Bub2/Cdc16 domain-containing proteins (TBC proteins) participate in wide range cellular processes. With computational approaches, 137 non-redundant TBC proteins from five model organisms were identified and classified into 13 subfamilies base on molecular evolutionary tree. This phylogenetic analysis provides useful functional annotation of newly-identified TBC proteins and guides for further experimentation.

引用

收藏

页码：505 / 509

页数：5

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