Ontogenesis of villi and fetal vessels in the human placenta

被引：14

作者：

Challier, JC ^{[1
]}

Vervelle, C ^{[1
]}

Uzan, S ^{[1
]}

机构：

[1] Univ Paris 06, Hop Tenon, UPRES EA2396, Paris, France

来源：

FETAL DIAGNOSIS AND THERAPY | 2001年 / 16卷 / 04期

关键词：

human placenta; growth factors; angiogenesis; villous branching;

D O I：

10.1159/000053914

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The ontogenesis of the villous and vascular arborescence in normal pregnancy is reviewed. The emergence of the villi and the fetal vessels is described from early pregnancy to term together with the specializations of the villi, vessels and capillaries observed in the last trimester, The expression, localization and role of the angiogenic growth factors (FGF, VEGF, PLGF, HGF) are described and discussed, Pathological pregnancies with hyper- and hypocapillarization are related to altered oxygenation, The potential roles of growth factors are presented and hypotheses proposed which may provide a molecular basis for the development of the most frequent placental pathologies. Copyright (C) 2001 S. Karger AG, Basel.

引用

页码：218 / 226

页数：9

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