Lipase-catalyzed condensation of erythritol and medium-chain fatty acids in acetonitrile with low water content

被引:17
作者
Adachi, S [1 ]
Nagae, K [1 ]
Matsuno, R [1 ]
机构
[1] Kyoto Univ, Grad Sch Agr, Div Appl Life Sci, Sakyo Ku, Kyoto 6068502, Japan
关键词
erythritol; erythritol fatty acid ester; lipase; surfactant; condensation;
D O I
10.1016/S1381-1177(98)00115-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Erythritol could be esterified with medium-chain fatty acids with carbon numbers of 7 to 12 by immobilized lipase from Candida antarctica in acetonitrile with low water content at 50 degrees C. The highest equilibrium conversion, 50%, of erythritol-lauric acid ester was achieved at a water content of about 1% (v/v). It was shown that the activity coefficients of the substrates, product and water would play an important role in determination of the equilibrium conversion. Continuous production of erythritol-lauric acid ester at a conversion of ca. 70% was realized using a packed-bed reactor without significant lowering of the conversion for at least 10 days. (C) 1999 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:21 / 27
页数:7
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