Obscure gastrointestinal bleeding and calcific aortic stenosis (Heyde's syndrome)

被引:9
作者
Floudas, Charalampos S. [1 ]
Moyssakis, Ioannis [2 ]
Pappas, Paris [3 ]
Gialafos, Elias J. [2 ]
Aessopos, Athanasios [1 ]
机构
[1] Univ Athens, Sch Med, Dept Internal Med 1, Laikon Hosp, Athens 11527, Greece
[2] Laikon Gen Hosp, Dept Cardiol, Athens, Greece
[3] Laikon Gen Hosp, Dept Radiol, Athens, Greece
关键词
calcific aortic stenosis; gastrointestinal bleeding; gastrointestinal angiodysplasia; Heyde's syndrome;
D O I
10.1016/j.ijcard.2007.04.147
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The coexistence of calcific aortic valve stenosis and obscure gastrointestinal bleeding secondary to intestinal angiodysplasias usually of the cecum and the ascending colon constitutes Heyde's syndrome. The pathophysiologic link between both entities has remained unclear so far but newer studies suggest that it is the result of subtle alterations in plasma coagulation factors. Cessation of the bleeding has followed replacement of the aortic valve. We describe a patient with recurrent obscure gastrointestinal bleeding, calcific aortic stenosis and intestinal angiodysplasias, and discuss the current literature. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:292 / 294
页数:3
相关论文
共 16 条
  • [1] Reversal of aortic stenosis, bleeding gastrointestinal angiodysplasia, and von Willebrand syndrome by aortic valve replacement
    Anderson, RP
    McGrath, K
    Street, A
    [J]. LANCET, 1996, 347 (9002) : 689 - 690
  • [2] Increased prevalence of aortic stenosis in patients with arteriovenous malformations of the gastrointestinal tract in Heyde syndrome
    Batur, P
    Stewart, WJ
    Isaacson, JH
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (15) : 1821 - 1824
  • [3] Lower gastrointestinal bleeding
    Bounds, BC
    Friedman, LS
    [J]. GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2003, 32 (04) : 1107 - +
  • [4] HEYDE EC, 1958, NEW ENGL J MED, V259, P196
  • [5] A prospective survey of patients with valvular heart disease in Europe:: The Euro Heart Survey on Valvular Heart Disease
    Iung, B
    Baron, G
    Butchart, EG
    Delahaye, F
    Gohlke-Bärwolf, C
    Levang, OW
    Tornos, P
    Vanoverschelde, JL
    Vermeer, F
    Boersma, E
    Ravaud, P
    Vahanian, A
    [J]. EUROPEAN HEART JOURNAL, 2003, 24 (13) : 1231 - 1243
  • [6] THE ASSOCIATION OF UNEXPLAINED GASTROINTESTINAL-BLEEDING WITH CALCIFIC AORTIC-STENOSIS
    KING, RM
    PLUTH, JR
    GIULIANI, ER
    [J]. ANNALS OF THORACIC SURGERY, 1987, 44 (05) : 514 - 516
  • [7] The bicuspid aortic valve - Adverse outcomes from infancy to old age
    Lewin, MB
    Otto, CM
    [J]. CIRCULATION, 2005, 111 (07) : 832 - 834
  • [8] MARGULIS AR, 1960, SURGERY, V48, P534
  • [9] Natowitz L, 1993, Acta Chir Belg, V93, P31
  • [10] Proteolysis of von Willebrand factor and shear stress-induced platelet aggregation in patients with aortic valve stenosis
    Pareti, FI
    Lattuada, A
    Bressi, C
    Zanobini, M
    Sala, A
    Steffan, A
    Ruggeri, ZM
    [J]. CIRCULATION, 2000, 102 (11) : 1290 - 1295