Hepatitis E virus: an underdiagnosed cause of chronic hepatitis in renal transplant recipients

被引:19
作者
Halleux, D. [2 ]
Kanaan, N. [2 ]
Kabamba, B. [3 ]
Thomas, I. [4 ]
Hassoun, Z. [1 ]
机构
[1] Catholic Univ Louvain, Clin Univ St Luc, Div Gastroenterol, B-1200 Brussels, Belgium
[2] Catholic Univ Louvain, Clin Univ St Luc, Div Nephrol, B-1200 Brussels, Belgium
[3] Catholic Univ Louvain, Clin Univ St Luc, Div Clin Biol, B-1200 Brussels, Belgium
[4] Belgium Sci Inst Publ Hlth, Brussels, Belgium
关键词
hepatitis E virus; immunosuppression; renal transplantation; chronic hepatitis; KIDNEY-TRANSPLANT; INFECTION; CIRRHOSIS; THERAPY; PATIENT;
D O I
10.1111/j.1399-3062.2011.00677.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
Hepatitis E virus (HEV) infection can evolve to chronic hepatitis in immunocompromised patients leading to rapidly progressive cirrhosis. Proper diagnosis is therefore important, as reducing immunosuppressive therapy can allow clearance of the virus. We report a case of chronic HEV infection in a renal transplant recipient that went undiagnosed for many years, discuss the therapeutic options, and review the current available literature.
引用
收藏
页码:99 / 102
页数:4
相关论文
共 13 条
[1]
Clemente-Casares P, 2003, EMERG INFECT DIS, V9, P448
[2]
Persistent Carriage of Hepatitis E Virus in Patients with HIV Infection. [J].
Dalton, Harry R. ;
Bendall, Richard P. ;
Keane, Frances E. ;
Tedder, Richard S. ;
Ijaz, Samreen .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (10) :1025-1027
[3]
Chronic hepatitis E with cirrhosis in a kidney-transplant recipient [J].
Gerolami, Rene ;
Moal, Valerie ;
Colson, Philippe .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (08) :859-860
[4]
Chronic hepatitis E virus infection in liver transplant recipients [J].
Haagsma, Elizabeth B. ;
van den Berg, Arie P. ;
Porte, Robert J. ;
Benne, Cornelis A. ;
Vennema, Harry ;
Reimerink, Johan H. J. ;
Koopmans, Marion P. G. .
LIVER TRANSPLANTATION, 2008, 14 (04) :547-553
[5]
Hepatitis E virus-related cirrhosis in kidney- and kidney-pancreas-transplant recipients [J].
Kamar, N. ;
Mansuy, J. -M. ;
Cointault, O. ;
Selves, J. ;
Abravanel, F. ;
Danjoux, M. ;
Otal, R. ;
Esposito, L. ;
Durand, D. ;
Izopet, J. ;
Rostaing, L. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2008, 8 (08) :1744-1748
[6]
Hepatitis E virus and chronic hepatitis in organ-transplant recipients. [J].
Kamar, Nassim ;
Selves, Janick ;
Mansuy, Jean-Michel ;
Ouezzani, Leila ;
Peron, Jean-Marie ;
Guitard, Joelle ;
Cointault, Olivier ;
Esposito, Laure ;
Abravanel, Florence ;
Danjoux, Marie ;
Durand, Dominique ;
Vinel, Jean-Pierre ;
Izopet, Jacques ;
Rostaing, Lionel .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 358 (08) :811-817
[7]
Factors Associated With Chronic Hepatitis in Patients With Hepatitis E Virus Infection Who Have Received Solid Organ Transplants [J].
Kamar, Nassim ;
Garrouste, Cyril ;
Haagsma, Elizabeth B. ;
Garrigue, Valerie ;
Pischke, Sven ;
Chauvet, Cecile ;
Dumortier, Jerome ;
Cannesson, Amelie ;
Cassuto-Viguier, Elisabeth ;
Thervet, Eric ;
Conti, Filomena ;
Lebray, Pascal ;
Dalton, Harry R. ;
Santella, Robert ;
Kanaan, Nada ;
Essig, Marie ;
Mousson, Christiane ;
Radenne, Sylvie ;
Roque-Afonso, Anne Marie ;
Izopet, Jacques ;
Rostaing, Lionel .
GASTROENTEROLOGY, 2011, 140 (05) :1481-1489
[8]
Ribavirin Therapy Inhibits Viral Replication on Patients With Chronic Hepatitis E Virus Infection [J].
Kamar, Nassim ;
Rostaing, Lionel ;
Abravanel, Florence ;
Garrouste, Cyril ;
Lhomme, Sebastien ;
Esposito, Laure ;
Basse, Gregoire ;
Cointault, Olivier ;
Ribes, David ;
Nogier, Marie Beatrice ;
Alric, Laurent ;
Peron, Jean Marie ;
Izopet, Jacques .
GASTROENTEROLOGY, 2010, 139 (05) :1612-1618
[9]
Influence of Immunosuppressive Therapy on the Natural History of Genotype 3 Hepatitis-E Virus Infection After Organ Transplantation [J].
Kamar, Nassim ;
Abravanel, Florence ;
Selves, Janick ;
Garrouste, Cyril ;
Esposito, Laure ;
Lavayssiere, Laurence ;
Cointault, Olivier ;
Ribes, David ;
Cardeau, Isabelle ;
Nogier, Marie Beatrice ;
Mansuy, Jean Michel ;
Muscari, Fabrice ;
Peron, Jean Marie ;
Izopet, Jacques ;
Rostaing, Lionel .
TRANSPLANTATION, 2010, 89 (03) :353-360
[10]
INTERFERON-ALPHA-INDUCED ACUTE RENAL-ALLOGRAFT REJECTION [J].
MAGNONE, M ;
HOLLEY, JL ;
SHAPIRO, R ;
SCANTLEBURY, V ;
MCCAULEY, J ;
JORDAN, M ;
VIVAS, C ;
STARZL, T ;
JOHNSON, JP .
TRANSPLANTATION, 1995, 59 (07) :1068-1070