A gene (Cargl) that regulates tissue resistance to Candida albicans maps to chromosome 14 of the mouse

被引：15

作者：

Ashman, RB ^{[1
]}

机构：

[1] Univ Queensland, Sch Dent, Brisbane, Qld 4072, Australia

[2] Univ Western Australia, Dept Pathol, Nedlands, WA 6097, Australia

来源：

MICROBIAL PATHOGENESIS | 1998年 / 25卷 / 06期

关键词：

Candida albicans; mice; susceptibility; resistance; genes;

D O I：

10.1006/mpat.1998.0240

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tissue susceptibility and resistance to infection with the yeast Candida albicans is genetically regulated. Analysis of the strain distribution pattern of the C. albicans resistance gene (Carg1) and additional gene and DNA segment markers in the AKXL recombinant inbred (RI) set showed that 13/15 RI strains were concordant for Carg1, Tcra and Rib1. Therefore, Carg1 is probably located within a 17 cM segment of chromosome 14, within approximately 4 cM of the other two genes. (C) 1998 Academic Press.

引用

页码：333 / 335

页数：3

共 7 条

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