Diagnostic accuracy of features predicting lower gastrointestinal malignancy: a colonoscopy database review of 10 603 Chinese patients

被引：20

作者：

Bai, Y. ^{[1
,2
,3
]}

Xu, C. ^{[3
]}

Zou, D. -W. ^{[1
,3
]}

Gao, J. ^{[1
]}

Li, Z. -S. ^{[1
,2
,3
]}

机构：

[1] Second Mil Med Univ, Changhai Hosp, Dept Gastroenterol, Shanghai 200433, Peoples R China

[2] Second Mil Med Univ, Ctr Clin Epidemiol & Evidence Based Med, Shanghai 200433, Peoples R China

[3] Second Mil Med Univ, Changhai Hosp, Digest Endoscopy Ctr, Shanghai 200433, Peoples R China

来源：

COLORECTAL DISEASE | 2011年 / 13卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Diagnostic test; alarm feature; colorectal cancer; colonoscopy; COLORECTAL-CANCER; SYMPTOMS; ASIA; RATIONALE; NEOPLASIA; RISK;

D O I：

10.1111/j.1463-1318.2010.02251.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Aim The diagnostic accuracy of colonoscopic features in predicting colorectal cancer (CRC) malignancy was studied. Method Consecutive patients who underwent first-time colonoscopy for lower gastrointestinal (GI) symptoms from 1998 to 2009 were identified. Gender, age, symptoms, endoscopic and pathologic findings were reviewed. Results There were 10 603 patients. The overall prevalence of malignancy was 3.0% (313). Among these, only 58% (181/313) had features indicative of tumour formation. The overall sensitivity and specificity was 9.6% and 94.1%, respectively. The overall positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 2.66, 0.96 and 2.77, respectively. Conclusion A large proportion of Chinese patients with CRC presented without features indicative of tumour formation.

引用

页码：658 / 662

页数：5

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