Absolute configuration of a novel glutamate receptor antagonist kaitocephalin

被引：43

作者：

Kobayashi, H

Shin-ya, K ^{[1
]}

Furihata, K

Hayakawa, Y

Seto, H

机构：

[1] Univ Tokyo, Inst Mol & Cell Biol, Bunkyo Ku, Tokyo 1130032, Japan

[2] Univ Tokyo, Div Agr & Agr Life Sci, Bunkyo Ku, Tokyo 1138657, Japan

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 24期

关键词：

kaitocephalin; absolute structure; AMPA antagonist; NMDA antagonist;

D O I：

10.1016/S0040-4039(01)00647-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The absolute cofiguration of kaitocephalin, a novel glutamate antagonist, was determined by NMR spectral analysis of a cyclic derivative of kaitocephalin and by the modified Mosher's method to be 2S,3S,4R,7R and 9S. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4021 / 4023

页数：3

共 4 条

[1] Absolute configuration of amphidinol 3, the first complete structure determination from amphidinol homologues: Application of a new configuration analysis based on carbon-hydrogen spin-coupling constants [J].