Selenocyclisations of homoallylic sulfonamides:: A highly stereoselective route to both cis- and trans-2,5-dihydropyrroles

被引：23

作者：

Jones, AD

Knight, DW

Redfern, AL

Gilmore, J

机构：

[1] Univ Nottingham, Dept Chem, Nottingham NG7 2RD, England

[2] Cardiff Univ, Dept Chem, Cardiff CF1 3TB, S Glam, Wales

[3] Eli Lilly & Co, Lilly Res Ctr, Windlesham GU20 6PH, Surrey, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 16期

基金：

英国工程与自然科学研究理事会;

关键词：

cyclisation; selenonium ions; pyrrolidines; sulfonamides;

D O I：

10.1016/S0040-4039(99)00380-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Overall 5-endo-trig selenocyclisations of homoallylic sulfonamides proceed smoothly and highly stereoselectively, under a selection of conditions, to give excellent yields of selenopyrrolidines and the related trans- or cis-2,5-dihydropyrroles, after oxidation and elimination. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：3267 / 3270

页数：4

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