A convenient synthesis of D-idose

被引：12

作者：

Dromowicz, M ^{[1
]}

Köll, P ^{[1
]}

机构：

[1] Univ Oldenburg, Dept Chem, D-26111 Oldenburg, Germany

来源：

CARBOHYDRATE RESEARCH | 1998年 / 308卷 / 1-2期

关键词：

1-deoxy-1-nitro-D-iditol; Nef reaction; D-idose; 1,6-anhydro-B-D-idopyranose; D-idosan;

D O I：

10.1016/S0008-6215(98)00048-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Addition of nitromethane to D-xylose leads to the formation of two epimeric deoxynitroalditols, namely 1-deoxy-1-nitro-D-iditol and 6-deoxy-6-nitro-L-glucitol. Conversion of the former, obtainable in good yield by direct crystallisation, by a modified Nef reaction in an argon atmosphere afforded 68% of D-idose, which may readily be converted into 1,6-anhydro-beta-D-idopyranose ("D-idosan"). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：169 / 171

页数：3

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