A modulatory role for facial expressions in prosopagnosia

被引:84
作者
de Gelder, BC
Frissen, I
Barton, J
Hadjikhani, N
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, NMR Ctr, Charlestown, MA 02129 USA
[2] Tilburg Univ, Cognit & Affect Neurosci Lab, NL-5000 LA Tilburg, Netherlands
[3] Beth Israel Deaconess Med Ctr, Dept Neurol, Boston, MA 02215 USA
[4] Harvard Univ, Sch Med, Boston, MA 02215 USA
关键词
face recognition; amygdala; configural processes; inversion effect; emotion;
D O I
10.1073/pnas.1735530100
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Brain-damaged patients experience difficulties in recognizing a face (prosopagnosics), but they can still recognize its expression. The dissociation between these two face-related skills has served as a keystone of models of face processing. We now report that the presence of a facial expression can influence face identification. For normal viewers, the presence of a facial expression influences performance negatively, whereas for prosopagnosic patients, it improves performance dramatically. Accordingly, although prosopagnosic patients show a failure to process the facial configuration in the interest of face identification, that ability returns when the face shows an emotional expression. Accompanying brain-imaging results indicate activation in brain areas (amygdala, superior temporal sulcus, parietal cortex) outside the occipitotemporal areas normally activated for face identification and lesioned in these patients. This finding suggests a modulatory role of these areas in face identification that is independent of occipitotemporal face areas.
引用
收藏
页码:13105 / 13110
页数:6
相关论文
共 48 条
[1]   Neural systems for recognizing emotion [J].
Adolphs, R .
CURRENT OPINION IN NEUROBIOLOGY, 2002, 12 (02) :169-177
[2]   INVERSION AND CONFIGURATION OF FACES [J].
BARTLETT, JC ;
SEARCY, J .
COGNITIVE PSYCHOLOGY, 1993, 25 (03) :281-316
[3]   Lesions of the fusiform, face area impair perception of facial configuration in prosopagnosia [J].
Barton, JJS ;
Press, DZ ;
Keenan, JP ;
O'Connor, M .
NEUROLOGY, 2002, 58 (01) :71-78
[4]   Covert recognition in acquired and developmental prosopagnosia [J].
Barton, JJS ;
Cherkasova, M ;
O'Connor, M .
NEUROLOGY, 2001, 57 (07) :1161-1168
[5]   Electrophysiological studies of face perception in humans [J].
Bentin, S ;
Allison, T ;
Puce, A ;
Perez, E ;
McCarthy, G .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1996, 8 (06) :551-565
[6]  
BODAMER J, 1947, Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr, V118, P6, DOI 10.1007/BF00352849
[7]   Face context interferes with local part processing in a prosopagnosic patient [J].
Boutsen, L ;
Humphreys, GW .
NEUROPSYCHOLOGIA, 2002, 40 (13) :2305-2313
[8]   UNDERSTANDING FACE RECOGNITION [J].
BRUCE, V ;
YOUNG, A .
BRITISH JOURNAL OF PSYCHOLOGY, 1986, 77 :305-327
[9]   Neural mechanisms of empathy in humans: A relay from neural systems for imitation to limbic areas [J].
Carr, L ;
Iacoboni, M ;
Dubeau, MC ;
Mazziotta, JC ;
Lenzi, GL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (09) :5497-5502
[10]   Functional magnetic resonance imaging of human visual cortex during face matching: A comparison with positron emission tomography [J].
Clark, VP ;
Keil, K ;
Maisog, JM ;
Courtney, S ;
Ungerleider, LG ;
Haxby, JV .
NEUROIMAGE, 1996, 4 (01) :1-15