Spliceosome assembly in yeast: one ChIP at a time?

被引:8
作者
Nilsen, TW [1 ]
机构
[1] Case Western Reserve Univ, Sch Med, Ctr RNA Mol Biol, Cleveland, OH 44106 USA
关键词
D O I
10.1038/nsmb0705-571
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
When and how the spliceosome assembles on its substrates in living yeast cells has been unclear. It is now evident that the 'when' is during transcription; the 'how' remains debatable.
引用
收藏
页码:571 / 573
页数:4
相关论文
共 21 条
[1]   Functional association of U2 snRNP with the ATP-independent spliceosomal complex E [J].
Das, R ;
Zhou, ZL ;
Reed, R .
MOLECULAR CELL, 2000, 5 (05) :779-787
[2]   Modified nucleotides at the 5′ end of human U2 snRNA are required for spliceosomal E-complex formation [J].
Dönmez, G ;
Hartmuth, K ;
Lührmann, R .
RNA, 2004, 10 (12) :1925-1933
[3]  
GORNEMANN J, 2005, IN PRESS MOL CELL
[4]   Characterization of U4 and U6 interactions with the 5′ splice site using a S-cerevisiae in vitro trans-splicing system [J].
Johnson, TL ;
Abelson, J .
GENES & DEVELOPMENT, 2001, 15 (15) :1957-1970
[5]   Pre-mRNA splicing: Awash in a sea of proteins [J].
Jurica, MS ;
Moore, MJ .
MOLECULAR CELL, 2003, 12 (01) :5-14
[6]   Multiple links between transcription and splicing [J].
Kornblihtt, AR ;
De la Mata, M ;
Fededa, JP ;
Muñoz, MJ ;
Nogués, G .
RNA, 2004, 10 (10) :1489-1498
[7]   Modulation of P-element pre-mRNA splicing by a direct interaction between PSI and U1 snRNP 70K protein [J].
Labourier, E ;
Adams, MD ;
Rio, DC .
MOLECULAR CELL, 2001, 8 (02) :363-373
[8]  
LACADIE SA, 2005, IN PRESS MOL CELL
[9]   Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome [J].
Makarov, EM ;
Makarova, OV ;
Urlaub, H ;
Gentzel, M ;
Will, CL ;
Wilm, M ;
Lührmann, R .
SCIENCE, 2002, 298 (5601) :2205-2208
[10]   A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing [J].
Makarova, OV ;
Makarov, EM ;
Urlaub, H ;
Will, CL ;
Gentzel, M ;
Wilm, M ;
Lührmann, R .
EMBO JOURNAL, 2004, 23 (12) :2381-2391