Genetic Characterization of West Nile Virus Lineage 2, Greece, 2010

被引：175

作者：

Papa, Anna ^{[2
]}

Bakonyi, Tamas ^{[3
]}

Xanthopoulou, Kyriaki ^{[2
]}

Vazquez, Ana ^{[4
]}

Tenorio, Antonio ^{[4
]}

Nowotny, Norbert ^{[1
]}

机构：

[1] Univ Vet Med, Zoonoses & Emerging Infect Grp, Dept Pathobiol, A-1210 Vienna, Austria

[2] Aristotle Univ Thessaloniki, GR-54006 Thessaloniki, Greece

[3] Fac Vet Sci, Budapest, Hungary

[4] Inst Salud Carlos III, Majadahonda, Spain

来源：

EMERGING INFECTIOUS DISEASES | 2011年 / 17卷 / 05期

关键词：

AMINO-ACID SUBSTITUTION; VIRULENCE; SOUTHERN; CONFERS; HUMANS;

D O I：

10.3201/eid1705.101759

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We conducted a complete genome analysis of a West Nile virus detected in Culex pipiens mosquitoes during a severe outbreak of human West Nile disease in Greece 2010. The virus showed closest genetic relationship to the lineage 2 strain that emerged in Hungary in 2004; increased virulence may be associated with amino acid substitution H249P.

引用

页码：920 / 922

页数：3

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