Acromegaly secondary to growth hormone releasing hormone secretion

被引:7
作者
Agha, A
Farrell, L
Downey, P
Keeling, P
Leen, E
Sreenan, S
机构
[1] James Connolly Mem Hosp, Dept Endocrinol, Dublin, Ireland
[2] James Connolly Mem Hosp, Dept Gen Surg, Dublin, Ireland
[3] James Connolly Mem Hosp, Dept Histopathol, Dublin, Ireland
关键词
Acromegaly; Pituitary Tumour; Growth Hormone Release Hormone; Pegvisomant; Ectopic Secretion;
D O I
10.1007/BF02914554
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Acromegaly secondary to growth hormone releasing hormone (GHRH) secretion is exceptionally rare. Aim To report a case of acromegaly diagnosed in 1984 and assumed to be pituitary in origin. Sixteen years later, the cause was found to be a GHRH secreting neuroendocrine pancreatic tumour. Method A case report. Conclusion Although ectopic GHRH production is very rare, endocrinologists should be aware of this possibility in acromegaly patients if a pituitary tumour was not detected using pituitary imaging.
引用
收藏
页码:215 / 216
页数:2
相关论文
共 6 条
[1]  
CHADENAS D, 1985, PRESSE MED, V14, P2129
[2]   ECTOPIC ACROMEGALY [J].
FAGLIA, G ;
AROSIO, M ;
BAZZONI, N .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1992, 21 (03) :575-595
[3]   Pathophysiology and clinical aspects of the ectopic GH-releasing hormone syndrome [J].
Losa, M ;
vonWerder, K .
CLINICAL ENDOCRINOLOGY, 1997, 47 (02) :123-135
[4]   ECTOPIC SECRETION OF GROWTH HORMONE-RELEASING HORMONE IN MAN [J].
LOSA, M ;
SCHOPOHL, J ;
VONWERDER, K .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1993, 16 (01) :69-81
[5]   CIRCULATING GROWTH-HORMONE RELEASING-FACTOR CONCENTRATIONS IN NORMAL SUBJECTS AND PATIENTS WITH ACROMEGALY [J].
PENNY, ES ;
PENMAN, E ;
PRICE, J ;
REES, LH ;
SOPWITH, AM ;
WASS, JAH ;
LYTRAS, N ;
BESSER, GM .
BRITISH MEDICAL JOURNAL, 1984, 289 (6443) :453-455
[6]  
VONWERDER K, 1986, SCAND J GASTROE S119, V21, P283