Blood purification therapies using dextran sulfate cellulose columns liposorber and Selesorb

被引：22

作者：

Asahi, T ^{[1
]}

Yamamoto, T ^{[1
]}

Kutsuki, H ^{[1
]}

机构：

[1] Kaneka Corp, Med Dev Div, Kita Ku, Osaka 5308288, Japan

来源：

THERAPEUTIC APHERESIS AND DIALYSIS | 2003年 / 7卷 / 01期

关键词：

dextran sulfate cellulose column; familial hypercholesterolemia; peripheral arterial disease; focal segmental glomerulosclerosis; systemic lupus erythematosus;

D O I：

10.1046/j.1526-0968.2003.00018.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Liposorber is a column used for plasma purification that adsorbs low-density lipoproteins with high selectivity while Selesorb is a column that selectively adsorbs anti-DNA antibodies, anticardiolipin antibodies, and immune complexes. Both columns are packed with carriers. where a dextran sulfate ligand is bound to porous cellulose beads. Liposorber is used to treat familial hypercholesterolemia (FH), peripheral arterial disease (PAD), and focal segmental glomerulosclerosis (FGS): Selesorb is used to treat systemic lupus erythematosus (SLE). Treatment utilizing both columns is being used effectively in patients with refractory disease that is resistant to pharmacotherapy.

引用

页码：73 / 77

页数：5

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