Involvement of P1 adhesin in gliding motility of Mycoplasma pneumoniae as revealed by the inhibitory effects of antibody under optimized gliding conditions

被引:83
作者
Seto, S
Kenri, T
Tomiyama, T
Miyata, M [1 ]
机构
[1] Osaka City Univ, Grad Sch Sci, Dept Biol, Sumiyoshi Ku, Osaka 5588585, Japan
[2] PRESTO, JST, Sumiyoshi Ku, Osaka, Japan
[3] Natl Inst Infect Dis, Dept Bacterial Pathogenesis & Infect Control, Musashimurayama, Japan
[4] Tomiyama Labs, Nerima Ku, Tokyo, Japan
关键词
D O I
10.1128/JB.187.5.1875-1877.2005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
To examine the participation of P1 adhesin in gliding of Mycoplasma pneumoniae, we examined the effects of an anti-P1 monoclonal antibody on individual gliding mycoplasmas. The antibody reduced the gliding speed and removed the gliding cells from the glass over time in a con centration-dependent manner but had only a slight effect on nongliding cells, suggesting that the conformational changes of P1 adhesin and its displacement are involved in the gliding mechanism.
引用
收藏
页码:1875 / 1877
页数:3
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