DNA Damage: Placing BRCA1 in the Proper Context

被引：7

作者：

Aressy, Bernadette ^{[1
]}

Greenberg, Roger A. ^{[1
,2
]}

机构：

[1] Univ Penn, Dept Canc Biol, Philadelphia, PA 19104 USA

[2] Univ Penn, Dept Canc Biol, Abramson Family Canc Res Inst, Basser Res Ctr BRCA1 2,Perelman Sch Med, Philadelphia, PA 19104 USA

来源：

CURRENT BIOLOGY | 2012年 / 22卷 / 18期

关键词：

E3 LIGASE ACTIVITY; POLY(ADP-RIBOSE) POLYMERASE; TUMOR SUPPRESSION; FANCONI-ANEMIA; BINDING; REPAIR; INHIBITORS;

D O I：

10.1016/j.cub.2012.07.046

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：R806 / R808

页数：3

共 17 条

[1] Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase [J].

Bryant, HE ;

Schultz, N ;

Thomas, HD ;

Parker, KM ;

Flower, D ;

Lopez, E ;

Kyle, S ;

Meuth, M ;

Curtin, NJ ;

Helleday, T .

NATURE, 2005, 434 (7035) :913-917

[2] Binding and recognition in the assembly of an active BRCA1 /BARD1 ubiquitin-ligase complex [J].

Brzovic, PS ;

Keeffe, JR ;

Nishikawa, H ;

Miyamoto, K ;

Fox, D ;

Fukuda, M ;

Ohta, T ;

Klevit, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (10) :5646-5651

[3] BRCA1 Functions Independently of Homologous Recombination in DNA Interstrand Crosslink Repair [J].

Bunting, Samuel F. ;

Callen, Elsa ;

Kozak, Marina L. ;

Kim, Jung Min ;

Wong, Nancy ;

Lopez-Contreras, Andres J. ;

Ludwig, Thomas ;

Baer, Richard ;

Faryabi, Robert B. ;

Malhowski, Amy ;

Chen, Hua-Tang ;

Fernandez-Capetillo, Oscar ;

D'Andrea, Alan ;

Nussenzweig, Andre .

MOLECULAR CELL, 2012, 46 (02) :125-135

[4] BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance [J].

Drost, Rinske ;

Bouwman, Peter ;

Rottenberg, Sven ;

Boon, Ute ;

Schut, Eva ;

Klarenbeek, Sjoerd ;

Klijn, Christiaan ;

van der Heijden, Ingrid ;

van der Gulden, Hanneke ;

Wientjens, Ellen ;

Pieterse, Mark ;

Catteau, Aurelie ;

Green, Pete ;

Solomon, Ellen ;

Morris, Joanna R. ;

Jonkers, Jos .

CANCER CELL, 2011, 20 (06) :797-809

[5] Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy [J].

Farmer, H ;

McCabe, N ;

Lord, CJ ;

Tutt, ANJ ;

Johnson, DA ;

Richardson, TB ;

Santarosa, M ;

Dillon, KJ ;

Hickson, I ;

Knights, C ;

Martin, NMB ;

Jackson, SP ;

Smith, GCM ;

Ashworth, A .

NATURE, 2005, 434 (7035) :917-921

[6] Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers. [J].

Fong, Peter C. ;

Boss, David S. ;

Yap, Timothy A. ;

Tutt, Andrew ;

Wu, Peijun ;

Mergui-Roelvink, Marja ;

Mortimer, Peter ;

Swaisland, Helen ;

Lau, Alan ;

O'Connor, Mark J. ;

Ashworth, Alan ;

Carmichael, James ;

Kaye, Stan B. ;

Schellens, Jan H. M. ;

de Bono, Johann S. .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (02) :123-134

[7] Interaction of the fanconi anemia proteins and BRCA1 in a common pathway [J].

Garcia-Higuera, I ;

Taniguchi, T ;

Ganesan, S ;

Meyn, MS ;

Timmers, C ;

Hejna, J ;

Grompe, M ;

D'Andrea, AD .

MOLECULAR CELL, 2001, 7 (02) :249-262

[8] Loss of CHK1 function impedes DNA damage-induced FANCD2 monoubiquitination but normalizes the abnormal G2 arrest in Fanconi anemia [J].

Guervilly, Jean-Hugues ;

Mace-Aime, Gaetane ;

Rosselli, Filippo .

HUMAN MOLECULAR GENETICS, 2008, 17 (05) :679-689

[9] Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation [J].

Lin, SY ;

Li, KY ;

Stewart, GS ;

Elledge, SJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (17) :6484-6489

[10] BRCT repeats as phosphopeptide-binding modules involved in protein targeting [J].

Manke, IA ;

Lowery, DM ;

Nguyen, A ;

Yaffe, MB .

SCIENCE, 2003, 302 (5645) :636-639

← 1 2 →