The use of SIMS for uranium localization in biological research

被引：6

作者：

Amaral, A

Galle, P

Escaig, F

Cossonnet, C

Henge-Napoli, MH

Ansoborlo, E

Zhang, L

机构：

[1] SDOS, DPHD, IPSN, F-92265 Fontenay Aux Roses, France

[2] Univ Fed Rural Pernambuco, Recife, PE, Brazil

[3] Fac Med, INSERM, Biophys Lab, F-94010 Creteil, France

来源：

JOURNAL OF ALLOYS AND COMPOUNDS | 1998年 / 271卷

关键词：

SIMS; uranium; radiotoxicology; internal dosimetry;

D O I：

10.1016/S0925-8388(98)00016-4

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Secondary ion mass spectrometry (SIMS) enables the localization and isotopic determination in microvolume of all elements from the Mendeleyev table. Based an the ablation of samples by ion bombardment, the SIMS method allows rapid assessment of trace elements in biological samples. In this work, studies in vitro and in vivo have been carried out using, respectively, rat macrophages and lung tissue sections containing uranium oxides. Following the localization studies, the isotopic ratio between the U-235 and U-238 was measured. In the present work, analytical procedures and the potential of the SIMS in biological research are discussed. (C) 1998 Elsevier Science S.A.

引用

页码：19 / 24

页数：6

共 5 条

[1]

AMARAL A, 1997, J RADIAT NUCL CHEM, V266

[2] INVITRO CHEMICAL AND CELLULAR TESTS APPLIED TO URANIUM TRIOXIDE WITH DIFFERENT HYDRATION STATES [J].