MTHFR association with arteriosclerotic vascular disease?

被引：95

作者：

Fletcher, O ^{[1
]}

Kessling, AM ^{[1
]}

机构：

[1] Northwick Pk & St Marks NHS Trust, Imperial Coll Sch Med, Kennedy Galton Ctr, Harrow HA1 3UJ, Middx, England

来源：

HUMAN GENETICS | 1998年 / 103卷 / 01期

关键词：

D O I：

10.1007/s004390050776

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Complex diseases are far more common than diseases that follow simple Mendelian patterns of inheritance. Difficulties are experienced in the designing of experiments to dissect out the contribution of a single allele to a complex phenotype. We review the literature regarding a point mutation in methylenetetrahydrofolate reductase, a candidate gene for susceptibility to vascular diseases.

引用

页码：11 / 21

页数：11

共 55 条

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