Diagnostic Performance of an Executive Clock Drawing Task (CLOX) as a Screening Test for Mild Cognitive Impairment in Elderly Persons with Cognitive Complaints

被引：24

作者：

Forti, Paola ^{[1
]}

Olivelli, Valentina ^{[1
]}

Rietti, Elisa ^{[1
]}

Maltoni, Benedetta ^{[1
]}

Ravaglia, Giovanni ^{[1
]}

机构：

[1] Univ Bologna, Univ Hosp St Orsola Malpighi, Dept Internal Med Ageing & Nephrol, IT-40138 Bologna, Italy

来源：

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS | 2010年 / 30卷 / 01期

关键词：

Mild cognitive impairment; Clock drawing test; Executive control function; Screening test; Elderly population; MENTAL-STATE-EXAMINATION; DEMENTIA; TOOL;

D O I：

10.1159/000315515

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

030301 [社会学]; 100201 [内科学];

摘要：

Background: CLOX, a clock drawing test protocol uniquely sensitive to impairment of executive functions, has been proposed as a screening tool for mild cognitive impairment (MCI), but data about its diagnostic efficiency are lacking. Methods: There are data for 196 subjects, age >= 60 years, referred to a memory clinic for cognitive complaints. After extensive neuropsychological testing, 64 were diagnosed as cognitively normal and 132 with MCI. Results: At standard cutoffs, both CLOX subtests had a fair specificity (CLOX1 72%, CLOX2 92%) but unacceptably low values of sensitivity (CLOX1 54%, CLOX2 28%) and likelihood ratio (CLOX1 1.91, CLOX2 3.59) for MCI. The use of different cutoffs or the combination of CLOX with the Mini-Mental State Examination (MMSE) did not statistically increase diagnostic efficiency. Conclusion: CLOX, either alone or in combination with MMSE, is not a useful screening test for MCI in a clinical setting. Copyright (C) 2010 S. Karger AG, Basel

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页码：20 / 27

页数：8

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