Progressive multifocal leukoencephalopathy

被引：57

作者：

Berger, Joseph R. ^{[1
]}

机构：

[1] Univ Kentucky, Coll Med, Dept Neurol, Kentucky Clin L 445, Lexington, KY 40536 USA

来源：

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2007年 / 7卷 / 06期

关键词：

D O I：

10.1007/s11910-007-0072-9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Progressive multifocal leukoencephalopathy (PML) was a rare disease until the advent of the HIV/AIDS pandemic. Recent interest in the disorder has been spurred by its appearance in patients treated with the monoclonal antibodies natalizumab and rituximab. Unless the accompanying underlying immune deficit can be reversed, PML typically progresses to death fairly rapidly. Treatment directed against the JC virus has been unhelpful, but an increased understanding of disease pathogenesis may result in effective therapeutic strategies.

引用

页码：461 / 469

页数：9

共 95 条

[1] Activities of various compounds against murine and primate polyomaviruses [J].

Andrei, G ;

Snoeck, R ;

Vandeputte, M ;

DeClercq, E .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (03) :587-593

[2] Contract enhancement in progressive multifocal leukoencephalopathy:: a predictive factor for long-term survival? [J].

Arbusow, V ;

Strupp, M ;

Pfister, HW ;

Seelos, KC ;

Brückmann, H ;

Brandt, T .

JOURNAL OF NEUROLOGY, 2000, 247 (04) :306-308

[3] PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY - A HITHERTO UNRECOGNIZED COMPLICATION OF CHRONIC LYMPHATIC LEUKAEMIA AND HODGKINS DISEASE [J].

ASTROM, KE ;

MANCALL, EL ;

RICHARDSON, EP .

BRAIN, 1958, 81 (01) :93-&

[4]

BAUER W, 1969, NEUROLOGY, V19, P287

[5] PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY AND CYTARABINE - REMISSION WITH TREATMENT [J].

BAUER, WR ;

TUREL, AP ;

JOHNSON, KP .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1973, 226 (02) :174-196

[6] JC virus detection in bodily fluids: Clues to transmission [J].

Berger, Joseph R. ;

Miller, Craig S. ;

Mootoor, Yunanan ;

Avdiushko, Sergei A. ;

Kryscio, Richard J. ;

Zhu, Hua .

CLINICAL INFECTIOUS DISEASES, 2006, 43 (01) :E9-E12

[7] Progressive multifocal leukoencephalopathy and natalizumab - Unforeseen consequences [J].

Berger, JR ;

Koralnik, IJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (04) :414-416

[8] Progressive multifocal leukoencephalopathy in patients with HIV infection [J].

Berger, JR ;

Pall, L ;

Lanska, D ;

Whiteman, M .

JOURNAL OF NEUROVIROLOGY, 1998, 4 (01) :59-68

[9] PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN HIV-1-INFECTED CHILDREN [J].

BERGER, JR ;

SCOTT, G ;

ALBRECHT, J ;

BELMAN, AL ;

TORNATORE, C ;

MAJOR, EO .

AIDS, 1992, 6 (08) :837-841

[10] Predictive factors for prolonged survival in acquired immunodeficiency syndrome-associated progressive multifocal leukoencephalopathy [J].

Berger, JR ;

Levy, RM ;

Flomenhoft, D ;

Dobbs, M .

ANNALS OF NEUROLOGY, 1998, 44 (03) :341-349

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