Antiplasmodial and antioxidant isofuranonaphthoquinones from the roots of Bulbine capitata

被引：29

作者：

Bezabih, M

Abegaz, BM

Dufall, K

Croft, K

Skinner-Adams, T

Davis, TME

机构：

[1] Univ Botswana, Dept Chem, Gaborone, Botswana

[2] Univ Western Australia, Royal Perth Hosp, Dept Med, Perth, WA 6009, Australia

[3] Univ Western Australia, Fremantle Hosp, Dept Med, Nedlands, WA 6009, Australia

来源：

PLANTA MEDICA | 2001年 / 67卷 / 04期

关键词：

Bulbine capitata; Asphodelaceae; roots; isofuranonaphthoquinones; antioxidant; antiplasmodial;

D O I：

10.1055/s-2001-14329

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The roots of B. capitata yielded the new compounds 5,8-dihydroxy-1 -tigloylmethylnaphtho[2,3-c]furan-4,9-dione, 1-acetoxymethyl-8-hydroxynaphtho[2,3-c]furan-4,9-dione, and 1-acetoxymethyl-5,8-dihydroxynaphtho[2,3-c]furan-4,9-dione, in addition to the known compounds chrysophanol, 10,10'-chrysophanol bianthrone, 8-hydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione, 5,8-dihydroxy-1-methylnaphtho[2.3-c]furan-4,9-dione, 5,8-dihydroxy-1-hydroxymethylnaphtho[2,3-c]furan-4,9-dione, and 8-hydroxy-5-methoxy-1-methylnaphtho[2,3-c]furan-4,9-dione, or 5-hydroxy-8-methoxy-1-methylnaphtho[2.3-c]furan-4,9-dione. The new as well as the known isofuranonaphthoquinones showed antioxidant and weak antiplasmodial activities.

引用

页码：340 / 344

页数：5

共 17 条

[1] Isofuranonaphthoquinones and phenolic and knipholone derivatives from the roots of Bulbine capitata [J].