A simple procedure for the synthesis of enantiopure α-acetoxy ketones

被引：20

作者：

Babudri, F ^{[1
]}

Fiandanese, V ^{[1
]}

Marchese, G ^{[1
]}

Punzi, A ^{[1
]}

机构：

[1] Univ Bari, Dipartmento Chim, Ctr CNR Studio Metodol Innovat Sintesi Organ, I-70126 Bari, Italy

来源：

TETRAHEDRON | 1999年 / 55卷 / 08期

关键词：

organocopper reagents; ketones; cross-coupling;

D O I：

10.1016/S0040-4020(99)00035-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cross-coupling reactions of alpha-acetoxy carboxylic acid chlorides with organocopper reagents, derived from Grignard reagents, cuprous bromide and lithium bromide, provide a simple and straightforward method for the synthesis of enantiopure alpha-acetoxy ketones. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2431 / 2440

页数：10

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