One-Step Preparation of Functionalized (E)-Vinylsilanes from Aldehydes

被引：23

作者：

Lim, Diane S. W. ^{[1
]}

Anderson, Edward A. ^{[1
]}

机构：

[1] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 18期

基金：

英国工程与自然科学研究理事会;

关键词：

CROSS-COUPLING REACTIONS; RUTHENIUM-CATALYZED HYDROSILYLATION; STEREOSELECTIVE-SYNTHESIS; TERMINAL ALKYNES; ORGANIC-SYNTHESIS; (E)-1-ALKENYLBORONIC ESTERS; SILAFUNCTIONAL COMPOUNDS; ASYMMETRIC-SYNTHESIS; SILICON; REAGENTS;

D O I：

10.1021/ol201833u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalized (E)-vinylsilanes have been prepared in one step from a wide range of aldehydes, via a chromium(II)-mediated olefination with novel dihalomethylsilane reagents, in moderate to excellent yields and with excellent stereoselectivity.

引用

收藏

页码：4806 / 4809

页数：4

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