Cerebral correlates of motor imagery of normal and precision gait

被引:154
作者
Bakker, M. [1 ,2 ]
De Lange, F. P. [1 ]
Helmich, R. C. [1 ,2 ]
Scheeringa, R. [1 ]
Bloem, B. R. [2 ]
Toni, I. [1 ,3 ]
机构
[1] Radboud Univ Nijmegen, FC Donders Ctr Cognit Neuroimaging, NL-6525 ED Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Neurol, Nijmegen, Netherlands
[3] Univ Nijmegen St Radboud Hosp, Nijmegen Inst Cognit & Informat, NL-6500 HB Nijmegen, Netherlands
关键词
action simulation; functional magnetic resonance imaging; locomotion; precision walking; superior parietal lobule;
D O I
10.1016/j.neuroimage.2008.03.020
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We have examined the cerebral structures involved in motor imagery of normal and precision gait (i.e., gait requiring precise foot placement and increased postural control). We recorded cerebral activity with functional magnetic resonance imaging while subjects imagined walking along paths of two different widths (broad, narrow) that required either normal gait, or exact foot placement and increased postural control. We used a matched visual imagery (VI) task to assess the motor specificity of the effects, and monitored task performance by recording imagery times, eye movements, and electromyography during scanning. In addition, we assessed the effector specificity of MI of gait by comparing our results with those of a previous study on MI of hand movements. We found that imagery times were longer for the narrow path during MI, but not during VI, suggesting that MI was sensitive to the constraints imposed by a narrow walking path. Moreover, MI of precision gait resulted in increased cerebral activity and effective connectivity within a network involving the superior parietal lobules, the dorsal precentral gyri, and the right middle occipital gyrus. Finally, the cerebral responses to MI of gait were contiguous to but spatially distinct from regions involved in MI of hand movements. These results emphasize the role of cortical structures outside primary motor regions in imagining locomotion movements when accurate foot positioning and increased postural control is required. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:998 / 1010
页数:13
相关论文
共 95 条
[1]   A method for removing imaging artifact from continuous EEG recorded during functional MRI [J].
Allen, PJ ;
Josephs, O ;
Turner, R .
NEUROIMAGE, 2000, 12 (02) :230-239
[3]  
ARMSTRONG DM, 1988, J PHYSIOL-LONDON, V405, P1, DOI 10.1113/jphysiol.1988.sp017319
[4]   Multimodal image coregistration and partitioning - A unified framework [J].
Ashburner, J ;
Friston, K .
NEUROIMAGE, 1997, 6 (03) :209-217
[5]   Extrastriate body area in human occipital cortex responds to the performance of motor actions [J].
Astafiev, SV ;
Stanley, CM ;
Shulman, GL ;
Corbetta, M .
NATURE NEUROSCIENCE, 2004, 7 (05) :542-548
[6]   Motor imagery of gait: a quantitative approach [J].
Bakker, M. ;
de Lange, F. P. ;
Stevens, J. A. ;
Toni, I. ;
Bloem, B. R. .
EXPERIMENTAL BRAIN RESEARCH, 2007, 179 (03) :497-504
[7]   Action prediction in the cerebellum and in the parietal lobe [J].
Blakemore, SJ ;
Sirigu, A .
EXPERIMENTAL BRAIN RESEARCH, 2003, 153 (02) :239-245
[8]   Evidence for a spinal stepping generator in man [J].
Bussel, B ;
RobyBrami, A ;
Neris, OR ;
Yakovleff, A .
PARAPLEGIA, 1996, 34 (02) :91-92
[9]   INVOLUNTARY STEPPING AFTER CHRONIC SPINAL-CORD INJURY - EVIDENCE FOR A CENTRAL RHYTHM GENERATOR FOR LOCOMOTION IN MAN [J].
CALANCIE, B ;
NEEDHAMSHROPSHIRE, B ;
JACOBS, P ;
WILLER, K ;
ZYCH, G ;
GREEN, BA .
BRAIN, 1994, 117 :1143-1159
[10]   Control of goal-directed and stimulus-driven attention in the brain [J].
Corbetta, M ;
Shulman, GL .
NATURE REVIEWS NEUROSCIENCE, 2002, 3 (03) :201-215