Floating electrode optoelectronic tweezers: Light-driven dielectrophoretic droplet manipulation in electrically insulating oil medium

被引：48

作者：

Park, Sungyong ^{[1
]}

Pan, Chenlu ^{[1
]}

Wu, Ting-Hsiang ^{[2
]}

Kloss, Christoph ^{[3
]}

Kalim, Sheraz ^{[4
,5
]}

Callahan, Caitlin E. ^{[4
,5
]}

Teitell, Michael ^{[4
,5
]}

Chiou, Eric P. Y. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Mech & Aerosp Engn, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, Dept Elect Engn, Los Angeles, CA 90095 USA

[3] Johannes Kepler Univ Linz, Inst Fluid Mech & Heat Transfer, A-4040 Linz, Austria

[4] Univ Calif Los Angeles, Dept Pathol, Calif NanoSyst Inst,Ctr Cell Control, Broad Inst Regenerat Med & Stem Cell Res, Los Angeles, CA 90095 USA

[5] Univ Calif Los Angeles, Jonsson Comprehens Canc Ctr, Los Angeles, CA 90095 USA

来源：

APPLIED PHYSICS LETTERS | 2008年 / 92卷 / 15期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1063/1.2906362

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We report an optical actuation mechanism, floating electrode optoelectronic tweezers (FEOET). FEOET enables light-driven transport of aqueous droplets immersed in electrically insulating oil on a featureless photoconductive glass layer with direct optical images. We demonstrate that a 681 mu m de-ionized water droplet immersed in corn oil medium is actuated by a 3.21 mu W laser beam with an average intensity as low as 4.08 mu W/mm(2) at a maximum speed of 85.1 mu m/s on a FEOET device. FEOET provides a promising platform for massively parallel droplet manipulation with optical images on low cost, silicon-coated glass. The FEOET device structure, fabrication, working principle, numerical simulations, and operational results are presented in this letter. (C) 2008 American Institute of Physics.

引用

页数：3

共 16 条

[1] Multiphase electropatterning of cells and biomaterials [J].

Albrecht, Dirk R. ;

Underhill, Gregory H. ;

Mendelson, Avital ;

Bhatia, Sangeeta N. .

LAB ON A CHIP, 2007, 7 (06) :702-709

[2]

[Anonymous], 2005, ANGEW CHEM, DOI DOI 10.1002/ANGE.200462226

[3] Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: Criteria to identify the third liquid and validation with protein crystallization [J].

Chen, Delai L. ;

Li, ang Li ;

Reyes, Sebastian ;

Adamson, David N. ;

Ismagilov, Rustem F. .

LANGMUIR, 2007, 23 (04) :2255-2260

[4] Light actuation of liquid by optoelectrowetting [J].

Chiou, PY ;

Moon, H ;

Toshiyoshi, H ;

Kim, CJ ;

Wu, MC .

SENSORS AND ACTUATORS A-PHYSICAL, 2003, 104 (03) :222-228

[5]

Chiou PY, 2005, NATURE, V436, P370, DOI [10.1038/nature03831, 10.1038/nature0383l]

[6] On-line laser Raman spectroscopic probing of droplets engineered in microfluidic devices [J].

Cristobal, Galder ;

Arbouet, Laurence ;

Sarrazin, Flavie ;

Talaga, David ;

Bruneel, Jean-Luc ;

Joanicot, Mathieu ;

Servant, Laurent .

LAB ON A CHIP, 2006, 6 (09) :1140-1146

[7] Continuous segmented-flow polymerase chain reaction for high-throughput miniaturized DNA amplification [J].

Curcio, M ;

Roeraade, J .

ANALYTICAL CHEMISTRY, 2003, 75 (01) :1-7

[8]

Jones T.B., 2005, Electromechanics of particles

[9] Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics [J].

Lee, CC ;

Sui, GD ;

Elizarov, A ;

Shu, CYJ ;

Shin, YS ;

Dooley, AN ;

Huang, J ;

Daridon, A ;

Wyatt, P ;

Stout, D ;

Kolb, HC ;

Witte, ON ;

Satyamurthy, N ;

Heath, JR ;

Phelps, ME ;

Quake, SR ;

Tseng, HR .

SCIENCE, 2005, 310 (5755) :1793-1796

[10] Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: Comparing theory and experiments [J].

Li, Liang ;

Boedicker, James Q. ;

Ismagilov, Rustem F. .

ANALYTICAL CHEMISTRY, 2007, 79 (07) :2756-2761

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