Molecular cloning and sequence analysis of the chick melanocortin 1-receptor gene

被引：60

作者：

Takeuchi, S

Suzuki, H

Hirose, S

Yabuuchi, M

Sato, C

Yamamoto, H

Takahashi, S

机构：

[1] SUPERMOL SCI DIV,MOL ELECT SECT,ELECTROMECH LAB,TSUKUBA,IBARAKI 305,JAPAN

[2] TOHOKU UNIV,FAC SCI,INST BIOL,SENDAI,MIYAGI 980,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1996年 / 1306卷 / 2-3期

关键词：

melanocortin; 1-receptor; genomic DNA sequencing; (chicken);

D O I：

10.1016/0167-4781(96)00026-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The chick melanocortin 1-receptor gene was isolated. It is found to be an intronless gene encoding a 314 amino acid protein, sharing 64% identity with mammalian counterparts. A cis-element responsible for melanocyte-specific transcription is found in its 5' upstream region. It is probable that the expression of the receptor in melanocytes is closely correlated with that of melanogenesis-related genes.

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页码：122 / 126

页数：5

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