Mechanisms of disease: Myocardial reperfusion injury

被引:2504
作者
Yellon, Derek M. [1 ]
Hausenloy, Derek J. [1 ]
机构
[1] UCL Hosp & Med Sch, Hatter Cardiovasc Inst, London WC1E 6HX, England
关键词
D O I
10.1056/NEJMra071667
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Lethal reperfusion injury is a paradoxical type of myocardial injury caused by the restoration of coronary blood flow after an ischemic episode. This review focuses on the mechanisms of the injury, on attempts to protect the heart against it, and on promising new approaches to cardioprotection during percutaneous coronary intervention. Copyright © 2007 Massachusetts Medical Society.
引用
收藏
页码:1121 / 1135
页数:15
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