Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7

被引：14

作者：

Whittam, TS ^{[1
]}

Reid, SD ^{[1
]}

Selander, RK ^{[1
]}

机构：

[1] Penn State Univ, Inst Mol Evolutionary Genet, University Pk, PA 16802 USA

来源：

EMERGING INFECTIOUS DISEASES | 1998年 / 4卷 / 04期

关键词：

D O I：

10.3201/eid0404.980411

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecular evolution.

引用

页码：615 / 617

页数：3

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