A self-assembled microlensing rotational probe

被引:26
作者
Brody, JP [1 ]
Quake, SR [1 ]
机构
[1] CALTECH, Dept Appl Phys, Pasadena, CA 91125 USA
基金
美国国家科学基金会;
关键词
D O I
10.1063/1.122977
中图分类号
O59 [应用物理学];
学科分类号
摘要
A technique to measure microscopic rotational motion is presented. When a small fluorescent polystyrene microsphere is attached to a larger polystyrene microsphere, the larger sphere acts as a lens for the smaller microsphere and provides an optical signal that is a strong function of the azimuthal angle. We demonstrate the technique by measuring the rotational diffusion constant of the microsphere in solutions of varying viscosity and discuss the feasibility of using this probe to measure rotational motion of biological systems. (C) 1999 American Institute of Physics. [S0003-6951(99)03401-4].
引用
收藏
页码:144 / 146
页数:3
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