Immunogenicity and safety of influenza vaccination in children with inflammatory bowel disease

被引:57
作者
deBruyn, Jennifer C. C. [1 ,2 ]
Hilsden, Robert [2 ,3 ]
Fonseca, Kevin [4 ]
Russell, Margaret L. [2 ]
Kaplan, Gilaad G. [2 ,3 ]
Vanderkooi, Otto [5 ]
Wrobel, Iwona [1 ]
机构
[1] Univ Calgary, Alberta Childrens Hosp, Div Paediat Gastroenterol & Nutr, Dept Paediat,Fac Med, Calgary, AB T3B 6A8, Canada
[2] Univ Calgary, Dept Community Hlth Sci, Fac Med, Calgary, AB T3B 6A8, Canada
[3] Univ Calgary, Div Gastroenterol, Fac Med, Dept Med, Calgary, AB T3B 6A8, Canada
[4] Div Virol, Prov Lab Publ Hlth Microbiol, Calgary, AB, Canada
[5] Univ Calgary, Div Paediat Infect Dis, Dept Paediat, Alberta Childrens Hosp,Fac Med, Calgary, AB T3B 6A8, Canada
关键词
inflammatory bowel disease; influenza vaccine; immunogenicity; ANTIBODY-RESPONSE; RESPIRATORY VIRUSES; IMMUNE-RESPONSES; CROHNS-DISEASE; ACTIVITY INDEX; IMMUNIZATION; INFECTIONS; EFFICACY; CELL; VALIDATION;
D O I
10.1002/ibd.21706
中图分类号
R57 [消化系及腹部疾病];
学科分类号
100201 [内科学];
摘要
Background: Protection against vaccine-preventable diseases is important in inflammatory bowel disease (IBD) because of increased susceptibility and severity of infection with immunosuppressive therapy. However, immunosuppressive therapy may affect vaccine response. This study aimed to evaluate immunogenicity and safety of influenza vaccination in children with IBD.
引用
收藏
页码:25 / 33
页数:9
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