Mass distribution of free, intranasally administered influenza vaccine in a public school system

被引:80
作者
Carpenter, L. Rand
Lott, John
Lawson, Brian M.
Hall, Stephanie
Craig, Allen S.
Schaffner, William
Jones, Timothy F.
机构
[1] Tennessee Dept Hlth, Commicable & Environm Dis Serv, Nashville, TN 37247 USA
[2] Ctr Dis Control & Prevent, Epidem Intelligence Serv, Atlanta, GA USA
[3] Knox Cty Hlth Dept, Knoxville, TN USA
[4] Vanderbilt Univ, Sch Med, Dept Prevent Med, Nashville, TN USA
关键词
influenza; immunizations; live attenuated influenza vaccine vaccine; herd immunity;
D O I
10.1542/peds.2006-2603
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
OBJECTIVE. School-based influenza vaccination programs are a potentially important method of protecting the community against influenza. We evaluated the feasibility and success of a large, school-based influenza vaccination campaign. METHODS. On-site administration of intranasally administered, live attenuated influenza vaccine was offered to all students and staff members in a large, metropolitan public school system in October to December 2005. We evaluated vaccine coverage levels, resources expended, and physician and parent attitudes and knowledge. RESULTS. Of 53 420 public school students, 24 198 were vaccinated with live attenuated influenza vaccine. Of 5841 school staff members, 3626 were vaccinated with live attenuated influenza vaccine or inactivated influenza vaccine. The proportions of students vaccinated were 56% among elementary schools, 45% among middle schools, and 30% among high schools. Schools with larger proportions of black or low-income families had lower vaccine coverage levels. The health department and school system expended 6900 person-hours during the campaign, and various health department clinics were closed for a total of 84 half-days. Community physicians were supportive of the campaign and frequently advised participation for eligible patients. Some physicians had misunderstandings about live attenuated influenza vaccine contraindications. Concern about adverse effects, having asthma, negative physician advice, and nonparticipation in any vaccination program were common reasons for students not participating. CONCLUSIONS. This influenza vaccination campaign in a large public school system achieved relatively high vaccine coverage levels but required a substantial resource commitment from the local health department. This evaluation has critical implications for the ongoing debate regarding immunization policies for school-aged children and preparedness plans for pandemic influenza.
引用
收藏
页码:E172 / E178
页数:7
相关论文
共 28 条
[1]  
Dooley Samuel W., 2008, Morbidity and Mortality Weekly Report, V57, P1
[2]  
Anonymous, 2005, Morbidity and Mortality Weekly Report, V54, P765
[3]   Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood:: ISAAC Phases One and Three repeat multicountry cross-sectional surveys [J].
Asher, M. Innes ;
Montefort, Stephen ;
Bjorksten, Bengt ;
Lai, Christopher K. W. ;
Strachan, David P. ;
Weiland, Stephan K. ;
Williams, Hywel .
LANCET, 2006, 368 (9537) :733-743
[4]   Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 years [J].
Belshe, RB ;
Nichol, KL ;
Black, SB ;
Shinefield, H ;
Cordova, J ;
Walker, R ;
Hessel, C ;
Cho, I ;
Mendelman, PM .
CLINICAL INFECTIOUS DISEASES, 2004, 39 (07) :920-927
[5]   Current status of live attenuated influenza virus vaccine in the US [J].
Belshe, RB .
VIRUS RESEARCH, 2004, 103 (1-2) :177-185
[6]   The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children [J].
Belshe, RB ;
Mendelman, PM ;
Treanor, J ;
King, J ;
Gruber, WC ;
Piedra, P ;
Bernstein, DI ;
Hayden, FG ;
Kotloff, K ;
Zangwill, K ;
Iacuzio, D ;
Wolff, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (20) :1405-1412
[7]  
*CDCP, 1999, MMWR-MORBID MORTAL W, V48, P918
[8]  
*CDCP, 2000, MMWR-MORBID MORTAL W, V49, P908
[9]   Interdisciplinary epidemiologic and economic research needed to support a universal childhood influenza vaccination policy [J].
Coleman, Margaret S. ;
Washington, Michael L. ;
Orenstein, Walter A. ;
Gazmararian, Julie A. ;
Prill, Mila M. .
EPIDEMIOLOGIC REVIEWS, 2006, 28 :41-46
[10]   INFLUENZA-VIRUS INFECTIONS IN SEATTLE FAMILIES, 1975-1979 .2. PATTERN OF INFECTION IN INVADED HOUSEHOLDS AND RELATION OF AGE AND PRIOR ANTIBODY TO OCCURRENCE OF INFECTION AND RELATED ILLNESS [J].
FOX, JP ;
COONEY, MK ;
HALL, CE ;
FOY, HM .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1982, 116 (02) :228-242