Getting a grip: new insights for cell adhesion and traction

被引:18
作者
Lauffenburger, DA
Wells, A
机构
[1] MIT, Div Bioengn & Environment Hlth, Cambridge, MA 02139 USA
[2] MIT, Ctr Canc Res, Cambridge, MA 02139 USA
[3] Univ Pittsburgh, Sch Med, Dept Pathol, Pittsburgh, PA 15261 USA
关键词
D O I
10.1038/35074631
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A crucial aspect of cell function in tissues is the biophysical interactions of the cell with the surrounding extracellular matrix. A fascinating report in this issue offers a major advance in the techniques available for investigating how the transmission of cell-generated forces to an underlying substratum is regulated. Application of this approach should provide key insights into such force regulation during cell migration and matrix contraction.
引用
收藏
页码:E110 / E112
页数:3
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