The evolution of the type I interferons

被引:132
作者
Roberts, RM
Liu, LM
Guo, QT
Leaman, D
Bixby, J
机构
[1] Univ Missouri, Dept Anim Sci, Anim Sci Ctr, Columbia, MO 65211 USA
[2] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[3] Gemini Technol Inc, Cleveland, OH 44106 USA
关键词
D O I
10.1089/jir.1998.18.805
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
There are five recognized subtypes within the type I interferons (IFN), IFN-alpha, IFN-beta, IFN-delta, IFN-omega, and IFN-tau, although others may remain to be described, and the IFN-omega may have to be subdivided further because of their evident structural complexity. Together, they constitute an ancient family of intronless genes, possibly present in all vertebrates, THe IFNA/IFNB genes originated by duplication of a progenitor after the divergence of birds, most probably about 250 million years ago (MYA), The avian gene itself proceeded to duplicate to form a series of independent subtypes, The IFND, to date described only in the pig, arose from the IFNA lineage before the emergence of mammals about 180 MYA and might, therefore, be generally distributed in present day species. The IFNB, which occurs as a single gene in primates and rodents, have been duplicated in some other orders. Recent events have produced 10 or more genes in bovid species. The IFNA, which are clustered with the IFNW in humans and cattle, exist as multiple genes in all mammals so far examined as a result of a series of duplication events, some of which occurred recently and, therefore, independently in separate mammalian lineages. The IFNW diverged from the IFNA approximately 130 MYA, just prior to the emergence of mammals, and have continued to duplicate since then. The IFNT, which play a role in reproduction of ruminants, arose from an IFNW within the Artiodactyla suborder about 36 MYA and are found only in the suborder Ruminantia, These genes have also continued to duplicate to form an extensive family. Consequently, their involvement in early pregnancy is a feature of ruminants and not of other mammalian species.
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页码:805 / 816
页数:12
相关论文
共 54 条
[1]   Nomenclature of the human interferon proteins [J].
Allen, G ;
Diaz, MO .
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, 1996, 16 (02) :181-182
[2]   MOLECULAR-CLONING OF A GENE ENCODING PORCINE INTERFERON-BETA [J].
ARTURSSON, K ;
GOBL, A ;
LINDERSSON, M ;
JOHANSSON, M ;
ALM, G .
JOURNAL OF INTERFERON RESEARCH, 1992, 12 (03) :153-160
[3]   2 DISTINCT FAMILIES OF HUMAN AND BOVINE INTERFERON-ALPHA GENES ARE COORDINATELY EXPRESSED AND ENCODE FUNCTIONAL POLYPEPTIDES [J].
CAPON, DJ ;
SHEPARD, HM ;
GOEDDEL, DV .
MOLECULAR AND CELLULAR BIOLOGY, 1985, 5 (04) :768-779
[4]   CLONING AND STRUCTURAL-ANALYSIS OF 4 GENES ENCODING INTERFERON-OMEGA IN RABBIT [J].
CHARLIER, M ;
LHARIDON, R ;
BOISNARD, M ;
MARTAL, J ;
GAYE, P .
JOURNAL OF INTERFERON RESEARCH, 1993, 13 (05) :313-322
[5]  
De Maeyer E., 1988, INTERFERONS OTHER RE
[6]   Anti-HIV potential of a new interferon, interferon-tau (trophoblastin) [J].
DereuddreBosquet, N ;
Clayette, P ;
Martin, M ;
Mabondzo, A ;
Fretier, P ;
Gras, G ;
Martal, J ;
Dormont, D .
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY, 1996, 11 (03) :241-246
[7]   STRUCTURE OF THE HUMAN TYPE-I INTERFERON GENE-CLUSTER DETERMINED FROM A YAC CLONE CONTIG [J].
DIAZ, MO ;
POMYKALA, HM ;
BOHLANDER, SK ;
MALTEPE, E ;
MALIK, K ;
BROWNSTEIN, B ;
OLOPADE, OI .
GENOMICS, 1994, 22 (03) :540-552
[8]   THE MOLECULAR CELL BIOLOGY OF INTERFERON-GAMMA AND ITS RECEPTOR [J].
FARRAR, MA ;
SCHREIBER, RD .
ANNUAL REVIEW OF IMMUNOLOGY, 1993, 11 :571-611
[9]   The coevolution of gene family trees [J].
Fryxell, KJ .
TRENDS IN GENETICS, 1996, 12 (09) :364-369
[10]   CONCERTED EVOLUTION OF HUMAN INTERFERON ALPHA-GENES [J].
GILLESPIE, D ;
CARTER, W .
JOURNAL OF INTERFERON RESEARCH, 1983, 3 (01) :83-88