Capillary electrophoresis for the determination of organic acidurias in body fluids: A review

被引:14
作者
Garcia, A [1 ]
Barbas, C [1 ]
机构
[1] Univ San Pablo, Fac CC Expt & Salud, CEU, Madrid 28668, Spain
关键词
inborn errors; capillary electrophoresis; organic acids;
D O I
10.1515/CCLM.2003.115
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
A systematic review of the literature on capillary electrophoresis applied to short chain organic acid analysis in body fluids has been conducted with special interest on those acids related to inborn errors of metabolism. The technique is briefly described, as well as the choice of the main analytical parameters: sample pre-treatment, polarity, capillary type, background electrolyte, and detection. The applications described in the literature are listed and the main features of the technique are discussed.
引用
收藏
页码:755 / 761
页数:7
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