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Tumour biology - Weakening link to colorectal cancer?

被引：43
作者：
Barbier, M [1 ]
Attoub, S
Calvez, R
Laffargue, M
Jarry, A
Mareel, M
Altruda, F
Gespach, C
Wu, D
Lu, B
Hirsch, E
Wymann, MP
机构：
[1] Univ Fribourg, Inst Biochem, CH-1700 Fribourg, Switzerland
[2] Hop St Antoine, INSERM, U482, F-75571 Paris 12, France
[3] Hop Hotel Dieu, INSERM, U539, F-44035 Nantes, France
[4] State Univ Ghent, Expt Cancerol Lab, B-9000 Ghent, Belgium
[5] Univ Turin, Dipartimento Genet Biol & Biochim, I-10126 Turin, Italy
[6] Univ Connecticut, Dept Genet & Dev Biol, Farmington, CT 06030 USA
[7] Harvard Univ, Childrens Hosp, Sch Med, Boston, MA 02115 USA
来源：
NATURE | 2001年 / 413卷 / 6858期
关键词：
D O I：
10.1038/35101660
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
[No abstract available]
引用
收藏
页码：796 / 796
页数：1
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共 11 条
  • [1] Bifurcation of lipid and protein kinase signals of PI3Kγ to the protein kinases PKB and MAPK
    Bondeva, T
    Pirola, L
    Bulgarelli-Leva, G
    Rubio, I
    Wetzker, R
    Wymann, MP
    [J]. SCIENCE, 1998, 282 (5387) : 293 - 296
  • [2] Early functional effects of Clostridium difficile toxin A on human colonocytes
    Branka, JE
    Vallette, G
    Jarry, A
    BouHanna, C
    Lemarre, P
    Van, PN
    Laboisse, CL
    [J]. GASTROENTEROLOGY, 1997, 112 (06) : 1887 - 1894
  • [3] Analysis of the murine phosphoinositide 3-kinase γ gene
    Hirsch, E
    Wymann, MP
    Patrucco, E
    Tolosano, E
    Bulgarelli-Leva, G
    Marengo, S
    Rocchi, M
    Altruda, F
    [J]. GENE, 2000, 256 (1-2) : 69 - 81
  • [4] Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation
    Hirsch, E
    Katanaev, VL
    Garlanda, C
    Azzolino, O
    Pirola, L
    Silengo, L
    Sozzani, S
    Mantovani, A
    Altruda, F
    Wymann, MP
    [J]. SCIENCE, 2000, 287 (5455) : 1049 - 1053
  • [5] Roles of PLC-β2 and -β3 and PI3Kγ in chemoattractant-mediated signal transduction
    Li, Z
    Jiang, HP
    Xie, W
    Zhang, ZC
    Smrcka, AV
    Wu, DQ
    [J]. SCIENCE, 2000, 287 (5455) : 1046 - 1049
  • [6] Leukocytes navigate by compass:: roles of PI3Kγ and its lipid products
    Rickert, P
    Weiner, OD
    Wang, F
    Bourne, HR
    Servant, G
    [J]. TRENDS IN CELL BIOLOGY, 2000, 10 (11) : 466 - 473
  • [7] Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration
    Sasaki, T
    Irie-Sasaki, J
    Jones, RG
    Oliveira-dos-Santos, AJ
    Stanford, WL
    Bolon, B
    Wakeham, A
    Itie, A
    Bouchard, D
    Kozieradzki, I
    Joza, N
    Mak, TW
    Ohashi, PS
    Suzuki, A
    Penninger, JM
    [J]. SCIENCE, 2000, 287 (5455) : 1040 - 1046
  • [8] Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
    Sasaki, T
    Irie-Sasaki, J
    Horie, Y
    Bachmaier, K
    Fata, JE
    Li, M
    Suzuki, A
    Bouchard, D
    Ho, A
    Redston, M
    Gallinger, S
    Khokha, R
    Mak, TW
    Hawkins, PT
    Stephens, L
    Scherer, SW
    Tsao, M
    Penninger, JM
    [J]. NATURE, 2000, 406 (6798) : 897 - 902
  • [9] Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
    Walker, EH
    Pacold, ME
    Perisic, O
    Stephens, L
    Hawkins, PT
    Wymann, MP
    Williams, RL
    [J]. MOLECULAR CELL, 2000, 6 (04) : 909 - 919
  • [10] Structural insights into phosphoinositide 3-kinase catalysis and signalling
    Walker, EH
    Perisic, O
    Ried, C
    Stephens, L
    Williams, RL
    [J]. NATURE, 1999, 402 (6759) : 313 - 320
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