Apoptosis pathways in fungal growth, development and ageing

被引:118
作者
Hamann, Andrea [1 ]
Brust, Diana [1 ]
Osiewacz, Heinz D. [1 ]
机构
[1] Goethe Univ Frankfurt, Inst Mol Biosci, Dept Biosci & Cluster Excellence Macromol Complex, D-60438 Frankfurt, Germany
关键词
D O I
10.1016/j.tim.2008.03.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Apoptosis is one type of programmed cell death with great importance for development and homeostasis of multicellular organisms. Unexpectedly, during the past decade, evidence has been obtained for the existence of a basal apoptosis machinery in yeast, as unicellular fungus, and in some filamentous fungi, a group of microorganisms that are neither true unicellular nor true multicellular biological systems but something in between. Here, we review evidence for a role of apoptotic processes in fungal pathogenicity, competitiveness, propagation, ageing and lifespan control.
引用
收藏
页码:276 / 283
页数:8
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