Lymphocyte migration into tissue: The paradigm derived from CD4 subsets

被引：84

作者：

Bradley, LM ^{[1
]}

Watson, SR ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO,CTR CANC,LA JOLLA,CA 92093

来源：

CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 03期

关键词：

D O I：

10.1016/S0952-7915(96)80118-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The appropriate recirculation and migration of naive, effector and memory T cells into inflamed tissue are precisely controlled by adhesive interactions with vascular endothelium. Analyses of CD4 lymphocytes have indicated that naive and antigen-experienced cells exhibit distinctive patterns of homing and recirculation, and that subsets of cells preferentially localize in different anatomical locations as a consequence of previous antigen exposure and differences in adhesion receptor usage.

引用

页码：312 / 320

页数：9

共 64 条

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