Enzymatic characterization of TEM-63, a TEM-type extended spectrum β-lactamase expressed in three different genera of Enterobacteriaceae from South Africa

被引：9

作者：

Hanson, ND

Moland, ES

Pitout, JDD

机构：

[1] Creighton Univ, Dept Med Microbiol & Immunol, Sch Med, Omaha, NE 68178 USA

[2] Creighton Univ, Ctr Res AntiInfect & Biotechnol, Sch Med, Omaha, NE 68178 USA

[3] Creighton Univ, Sch Med, Dept Pediat, Omaha, NE 68178 USA

[4] Univ Orange Free State, Dept Med Microbiol, Bloemfontein, South Africa

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2001年 / 40卷 / 04期

关键词：

D O I：

10.1016/S0732-8893(01)00266-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The extended-spectrum beta -lactamase, TEM-63, was identified in three separate genera of South African isolates: Proteus mirabilis, Klebsiella pneumoniae, and Escherichia coli. This paper describes identification of the gene in these isolates and compares relative rates of hyrolysis between TEM-63 and other known ceftazidimases. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

收藏

页码：199 / 201

页数：3

相关论文

共 17 条

[1] NOVEL R-FACTOR BORNE BETA-LACTAMASE OF ESCHERICHIA-COLI CONFERING RESISTANCE TO CEPHALOSPORINS [J].

BAUERNFEIND, A ;

HORL, G .

INFECTION, 1987, 15 (04) :257-259

[2] SHV-7, A NOVEL CEFOTAXIME-HYDROLYZING BETA-LACTAMASE, IDENTIFIED IN ESCHERICHIA-COLI ISOLATES FROM HOSPITALIZED NURSING-HOME PATIENTS [J].

BRADFORD, PA ;

URBAN, C ;

JAISWAL, A ;

MARIANO, N ;

RASMUSSEN, BA ;

PROJAN, SJ ;

RAHAL, JJ ;

BUSH, K .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (04) :899-905

[3] Complexity and diversity of Klebsiella pneumoniae strains with extended-spectrum β-lactamases isolated in 1994 and 1996 at a teaching hospital in Durban, South Africa [J].

Essack, SY ;

Hall, LMC ;

Pillay, DG ;

McFadyen, ML ;

Livermore, DM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (01) :88-95

[4] Updated sequence information for TEM β-lactamase genes [J].

Goussard, S ;

Courvalin, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (02) :367-370

[5]

HANSON ND, 1998, 38 INT C ANT AG CHEM

[6] A natural polymorphism in beta-lactamase is a global suppressor [J].

Huang, WZ ;

Palzkill, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (16) :8801-8806

[7]

MANNIATIS T, 1982, MOL CLONING LAB MANU

[8] NOVEL PLASMID-MEDIATED BETA-LACTAMASE IN CLINICAL ISOLATES OF KLEBSIELLA-PNEUMONIAE MORE RESISTANT TO CEFTAZIDIME THAN TO OTHER BROAD-SPECTRUM CEPHALOSPORINS [J].

PETIT, A ;

SIROT, DL ;

CHANAL, CM ;

SIROT, JL ;

LABIA, R ;

GERBAUD, G ;

CLUZEL, RA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (05) :626-630

[9] EXTENDED-SPECTRUM BETA-LACTAMASES [J].

PHILIPPON, A ;

LABIA, R ;

JACOBY, G .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (08) :1131-1136

[10] β-lactamases responsible for resistance to expanded-spectrum cephalosporins in Klebsiella pneumoniae, Escherichia coli, and Proteus mirabilis isolates recovered in South Africa [J].

Pitout, JDD ;

Thomson, KS ;

Hanson, ND ;

Ehrhardt, AF ;

Moland, ES ;

Sanders, CC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (06) :1350-1354